It’s quite a change, you don’t make tweens since it auto tweens unless you set it to not auto tween (and you add tweens by pressing ctrl+L or remove with ctrl+k). There are symbols but you don’t use them at all compared to flash, and it depends which TB you have (one with node view or one without, if its without you have to do things quite differently). But it’s worth learning, absolutely watch tutorials as there are so many more tools and they work in such a different way, see here:
http://www.digitaltutors.com/tutorial/2187-Introduction-to-Toon-Boom-Harmony-Premium

Also i forgot to mention: TB has cam that can move in 3d SPACE by default, so you add a camera and can pan/zoom/rotate shots without moving anything (sorta like vcam) except its far better and by default.